NFKBIL2 (TONSL) Rabbit Polyclonal Antibody

SKU TA322397

Anti-TONSL Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 100-300; Positive control: Human ovarian cancer; Predicted cell location: Nucleus
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human tonsoku-like, DNA repair protein
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: tonsoku-like, DNA repair protein
• Database Link:
  NP_038460
  Q96HA7
• Background: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.?
• Synonyms: IKBR; NFKBIL2

Reference Data

• Protein Families: Transcription Factors