SOCS7 Rabbit Polyclonal Antibody
Anti-SOCS7 Rabbit Polyclonal Antibody
Product Datasheet for 'TA322370'
|Recommend Dilution||ELISA: 1:2000-5000, IHC: 1:50-200|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Synthetic peptide corresponding to a region derived from 6-20 amino acids of human suppressor of cytokine signaling 7|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Gene Name||suppressor of cytokine signaling 7|
|Background||The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin; growth hormone and leptin signaling by preventing STAT3 and STAT5 activation; sequestering them in the cytoplasm and reducing their binding to DNA.|
|Protein Families||Druggable Genome|
|Protein Pathways||Jak-STAT signaling pathway|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.