SOCS7 Rabbit Polyclonal Antibody

CAT#: TA322370

Anti-SOCS7 Rabbit Polyclonal Antibody


 Product Datasheet for 'TA322370'

USD 335.00


Availability*
In Stock

Size
    • 100 ul


Product images

Specifications

Product Data
Applications IHC
Recommend Dilution ELISA: 1:2000-5000, IHC: 1:50-200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 6-20 amino acids of human suppressor of cytokine signaling 7
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 1.1mg/ml
Purification Antigen affinity purification
Gene Name suppressor of cytokine signaling 7
Background The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin; growth hormone and leptin signaling by preventing STAT3 and STAT5 activation; sequestering them in the cytoplasm and reducing their binding to DNA.
Synonyms NAP4; NCKAP4
Reference Data
Protein Families Druggable Genome
Protein Pathways Jak-STAT signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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