LRIG1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human lung cancer Predicted cell location: Cytoplasm, Cell membrane |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 1073-1085 amino acids of Human leucine-rich repeats and immunoglobulin-like domains 1 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | leucine-rich repeats and immunoglobulin like domains 1 |
| Database Link | |
| Background | Leucine-rich repeats and immunoglobulin-like domains protein 1?is a?protein?that in humans is encoded by the?LRIG1?gene.?It encodes a?transmembrane protein?that has been shown to interact with receptor tyrosine kinases of the?EGFR-family?;?MET?and?RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases; through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. |
| Synonyms | LIG-1; LIG1 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Mondal, Kansal, Maroni et al
SSRN Journal (2020)
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