LRIG1 Rabbit Polyclonal Antibody

SKU
TA322346
Anti-LRIG1 Rabbit Polyclonal Antibody
  $305.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human lung cancer
Predicted cell location: Cytoplasm, Cell membrane
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 1073-1085 amino acids of Human leucine-rich repeats and immunoglobulin-like domains 1
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name leucine-rich repeats and immunoglobulin like domains 1
Database Link
Background Leucine-rich repeats and immunoglobulin-like domains protein 1?is a?protein?that in humans is encoded by the?LRIG1?gene.?It encodes a?transmembrane protein?that has been shown to interact with receptor tyrosine kinases of the?EGFR-family?;?MET?and?RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases; through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Synonyms LIG-1; LIG1
Reference Data
Protein Categories Membrane Proteins
Protein Families Transmembrane
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Documents
Resources

file-alt Citations

Lrig1 Regulates Epithelial to Mesenchyme Transition (EMT) in Pancreatic Duct Glands (PDG), an Epithelial Stem Cell Compartment Important in Regeneration and Cancer
Mondal, Kansal, Maroni et al
SSRN Journal (2020)
Snippet: Lrig1 TA322346 Origene Rabbit 1:100 Ki67 ab16667 abcam Rabbit 1:100 14-5698-82 invitrogen Rat 1:100 BrdU ab6326 abcam Rat 1:100 -smooth muscle actin A5228 Sigma Mouse 1:50 Laminin NB300-144 Novus Rabbit 1:100 Collagen IV PA1-28117 Invitrogen Rabbit 1:100
IHC
Showing 1-1 of 1 papers.
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