FOXL2 Rabbit Polyclonal Antibody

SKU TA322192

Anti-FOXL2 Rabbit Polyclonal Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 500-2000; WB positive control: Mouse brain and heart tissue
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 364-376 amino acids of Human forkhead box L2
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 50 kDa
• Gene Name: forkhead box L2
• Database Link:
  NP_075555
  P58012
• Background: This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance; and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
• Synonyms: BPES; BPES1; PFRK; PINTO; POF3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors