ACAD11 Rabbit Polyclonal Antibody

SKU TA322146

Anti-ACAD11 rabbit polyclonal antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Mouse kidney tissue, Mouse heart tissue lysates; IHC: 50-200; Positive control: Human esophagus cancer; Predicted cell location: Cytoplasm and Cell membrane
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 121-400 amino acids of human acyl-CoA dehydrogenase family, member 11
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 87 kDa
• Gene Name: acyl-CoA dehydrogenase family member 11
• Database Link:
  NP_115545
  Q709F0
• Background: The deduced full-length?ACAD11?protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable?ACAD11?expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11?associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed that?ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.
• Synonyms: ACAD-11

Reference Data

• Protein Families: Druggable Genome