MURF1 (TRIM63) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB:1/500-2000;IHC:1/50-200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide peptide corresponding to a region derived from 2-14 amino acids of human tripartite motif containing 63, E3 ubiquitin protein ligase |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 40 kDa |
| Gene Name | tripartite motif containing 63 |
| Database Link | |
| Background | This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins; myosin light chain; myosin binding protein; and for muscle-type creatine kinase. |
| Synonyms | IRF; MURF1; MURF2; RNF28; SMRZ |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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