PIWIL4 Rabbit Polyclonal Antibody

SKU TA322022

Anti-PIWIL4 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human colon cancer; Predicted cell location: Cytoplasm, Nucleus
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 546-838 amino acids of human piwi-like RNA-mediated gene silencing 4
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: piwi like RNA-mediated gene silencing 4
• Database Link:
  NP_689644
  Q7Z3Z4
• Background: PIWIL4 belongs to the Argonaute family of proteins; which function in development and maintenance of germline stem cells.It plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization; which is essential for the germline integrity.May be involved in the chromatin-modifying pathway by inducing 'Lys-9' methylation of histone H3 at some loci.
• Synonyms: HIWI2; MIWI2

Reference Data

• Protein Pathways: Dorso-ventral axis formation