COX18 Rabbit Polyclonal Antibody

SKU
TA322007
Anti-COX18 Rabbit Polyclonal Antibody
  $305.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 10-50
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 191-205 amino acids of Human cytochrome c oxidase assembly homolog 18 (yeast)
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name COX18 cytochrome c oxidase assembly factor
Database Link
Background COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane; an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.
Synonyms COX18HS
Reference Data
Protein Categories Membrane Proteins
Protein Families Transmembrane
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