DTX3 Rabbit Polyclonal Antibody

SKU TA322000

Anti-DTX3 Rabbit Polyclonal Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 200-1000; WB positive control: Human lymphoma tissue
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 248 amino acids of human deltex homolog 3 (Drosophila)
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 38 kDa
• Gene Name: deltex 3, E3 ubiquitin ligase
• Database Link:
  NP_848597
  Q8N9I9
• Background: DTX3 functions as an E3 ubiquitin ligase. Regulator of Notch signaling; a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch; depending on the developmental and cell context By similarity. Functions as an ubiquitin ligase protein in vitro; suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
• Synonyms: deltex3; RNF154

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Notch signaling pathway