AGR3 Rabbit Polyclonal Antibody

CAT#: TA321945

Anti-AGR3 Rabbit Polyclonal Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane 1-2: MCF7 cells human colon tissue Primary antibody: TA321945 (AGR3 Antibody) at dilution 1/150 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA321945 (AGR3 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA321945 (AGR3 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321945 (AGR3 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321945 (AGR3 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: A549 cell, HT-29 cell, Human next to colon cancer tissue lysates
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 22-166 amino acids of human anterior gradient 3 homolog (Xenopus laevis)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 19 kDa
• Gene Name: anterior gradient 3, protein disulphide isomerase family member
• Database Link:
  NP_789783
  Entrez Gene 403205 MouseEntrez Gene 155465 Human
  UniProt ID Q8TD06
• Background: Anterior gradient protein 3 homolog?is a?protein?that in humans is encoded by the?AGR3?gene. The deduced 166-amino acid protein has an N-terminal signal sequence. Fluorescence-tagged BCMP11 localized in secretory or endosome-like organelles in transfected breast carcinoma cell lines. Immunohistochemical analysis showed that expression of BCMP11 was restricted in normal tissues, with significant staining of only the epithelial lining of colonic mucosa. However, BCMP11 was detected in 43 of 58 (74%) breast cancer tissues tested, but not in normal breast ductal epithelial cells. In cancerous epithelial cells, BCMP11 localized to the cytoplasm.
• Synonyms: AG-3; AG3; BCMP11; hAG-3; HAG3; PDIA18

Reference Data

• Protein Families: Secreted Protein