AGR3 Rabbit Polyclonal Antibody

CAT#: TA321945

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Anti-AGR3 Rabbit Polyclonal Antibody

USD 380.00

4 Weeks

    • 100 ul


Product Data
Applications IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: A549 cell, HT-29 cell, Human next to colon cancer tissue lysates
IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 22-166 amino acids of human anterior gradient 3 homolog (Xenopus laevis)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 19 kDa
Gene Name anterior gradient 3, protein disulphide isomerase family member
Background Anterior gradient protein 3 homolog?is a?protein?that in humans is encoded by the?AGR3?gene. The deduced 166-amino acid protein has an N-terminal signal sequence. Fluorescence-tagged BCMP11 localized in secretory or endosome-like organelles in transfected breast carcinoma cell lines. Immunohistochemical analysis showed that expression of BCMP11 was restricted in normal tissues, with significant staining of only the epithelial lining of colonic mucosa. However, BCMP11 was detected in 43 of 58 (74%) breast cancer tissues tested, but not in normal breast ductal epithelial cells. In cancerous epithelial cells, BCMP11 localized to the cytoplasm.
Synonyms AG-3; AG3; BCMP11; hAG-3; HAG3; PDIA18
Reference Data
Protein Families Secreted Protein
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