KRT23 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 500-2000 WB positive control: Hela cell lysate IHC: 50-200 Positive control: Human gastric cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 1-250 amino acids of human keratin 23 (histone deacetylase inducible) |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 48 kDa |
| Gene Name | keratin 23 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. |
| Synonyms | CK23; HAIK1; K23 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
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| FAQs |
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Citations
Feedback repression of PPARα signaling by Let-7 microRNA
Yagai, Yan, Luo et al
Cell Rep (2021) 36 (6), 109506 DOI: 10.1016/j.celrep.2021.109506
Yagai, Yan, Luo et al
Cell Rep (2021) 36 (6), 109506 DOI: 10.1016/j.celrep.2021.109506
Cited by 19
AI Summary: OriGene’s MirLet7c-1 expression plasmid was used as a template to amplify the pre-let-7c-1 sequence for generating AAV vectors, enabling functional studies of let-7c-1 in the reported research.
Snippet: d Stu I restriction enzymes. For pre-let-7c-1 expression AAV, the 470 bp mouse genomic sequence around pre-let-7c-1 was amplified using custom primers (Table S3) from a MirLet7c-1 expression plasmid (Origene). The amplified fragments were cloned into pscAAV-ALBp-EGFP plasmid with Not I, Stu I, and EcoR V restriction enzymes. The plasmids were transfected into HEK293T cells to produce AAV8 vectors
Showing 1-1 of 1 papers.
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