ADAMTS5 Rabbit Polyclonal Antibody

SKU TA321799

Anti-ADAMTS5 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-100; Positive control: Human liver cancer; Predicted cell location: Secreted
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 529-541 amino acids of Human A disintegrin and metalloproteinase with thrombospondin motifs 5
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 5
• Database Link:
  NP_008969
  Q9UNA0
• Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules; including a propeptide region; a metalloproteinase domain; a disintegrin-like domain; and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs; and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan; a major proteoglycan of cartilage.
• Synonyms: ADAM-TS 5; ADAM-TS5; ADAM-TS 11; ADAMTS-5; ADAMTS-11; ADAMTS11; ADMP-2

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein