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RAD50 Rabbit Polyclonal Antibody

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SKU
TA321721
Anti-RAD50 Rabbit Polyclonal Antibody
  • TA321721 is a possible alternative to TA321722.
Size:
100 ul
Conjugation:
Unconjugated
  $305.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: 293T, Hela, K562, NIH/3T3 and RAW264.7 cells
IHC: 50-200
Positive control: Human colon cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 325-339 amino acids of Human RAD50 homolog (S. cerevisiae)
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 154 kDa
Gene Name RAD50 double strand break repair protein
Database Link
Background The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50; a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein; cooperating with its partners; is important for DNA double-strand break repair; cell cycle checkpoint activation; telomere maintenance; and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
Synonyms hRad50; NBSLD; RAD502
Reference Data
Protein Categories Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Homologous recombination, Non-homologous end-joining
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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