SSB Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Nucleus |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 100-105 amino acids of human Sjogren syndrome antigen B (autoantigen La) |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | Sjogren syndrome antigen B |
| Database Link | |
| Background | The protein encoded by this gene is involved in diverse aspects of RNA metabolism; including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion; processing 5' and 3' ends of pre-tRNA precursors; acting as an RNA chaperone; and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. |
| Synonyms | La; LARP3; SSB |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Systemic lupus erythematosus |
Reviews
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Citations
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