SSB Rabbit Polyclonal Antibody

SKU
TA321562
Anti-SSB Rabbit Polyclonal Antibody
  $305.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human colon cancer
Predicted cell location: Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 100-105 amino acids of human Sjogren syndrome antigen B (autoantigen La)
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name Sjogren syndrome antigen B
Database Link
Background The protein encoded by this gene is involved in diverse aspects of RNA metabolism; including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion; processing 5' and 3' ends of pre-tRNA precursors; acting as an RNA chaperone; and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.
Synonyms La; LARP3; SSB
Reference Data
Protein Categories Intracellular Proteins
Protein Families Stem cell - Pluripotency, Transcription Factors
Protein Pathways Systemic lupus erythematosus
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