GNAZ Rabbit Polyclonal Antibody

CAT#: TA321433

Anti-GNAZ Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human cerebrum tissue lysate Primary antibody: TA321433 (GNAZ Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA321433 (GNAZ Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA321433 (GNAZ Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human cerebrum tissue lysate
  IHC: 25-50
  Positive control: Human colorectal cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 4-18 amino acids of Human guanine nucleotide binding protein (G protein), alpha z polypeptide
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41 kDa
• Gene Name: G protein subunit alpha z
• Database Link:
  NP_002064
  Entrez Gene 14687 MouseEntrez Gene 25740 RatEntrez Gene 2781 Human
  UniProt ID P19086
• Background: Guanine nucleotide-binding protein G(z) subunit alpha?is a?protein?that in humans is encoded by the?GNAZgene. The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. GNAZ has been shown to interact with EYA2; RGS20 and RGS19.
• Synonyms: alpha z polypeptide; guanine nucleotide binding protein; guanine nucleotide binding protein (G protein); transducin alpha

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Long-term depression