ARF6 Rabbit Polyclonal Antibody

CAT#: TA321391

Anti-ARF6 Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-2: HepG2 cells 231 cells Primary antibody: TA321391 (ARF6 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA321391 (ARF6 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA321391 (ARF6 Antibody) at dilution 1/15, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HepG2 and 231 cells
  IHC: 10-50
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 162-175 amino acids of Human ADP-ribosylation factor 6
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: ADP ribosylation factor 6
• Database Link:
  NP_001654
  Entrez Gene 11845 MouseEntrez Gene 79121 RatEntrez Gene 382 Human
  UniProt ID P62330
• Background: This gene encodes a member of the human ARF gene family; which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane; and regulates vesicular trafficking; remodelling of membrane lipids; and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
• Synonyms: DKFZp564M0264

Reference Data

• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis