BDKRB2 Rabbit Polyclonal Antibody

CAT#: TA321168

Anti-BDKRB2 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: HUVEC cell lysate Primary antibody: TA321168 (BDKRB2 Antibody) at dilution 1/650 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 10 minutes

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321168 (BDKRB2 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321168 (BDKRB2 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HUVEC cell lysate
  IHC: 25-50
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 377-391 amino acids of human bradykinin receptor B2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: bradykinin receptor B2
• Database Link:
  NP_000614
  Entrez Gene 12062 MouseEntrez Gene 25245 RatEntrez Gene 624 Human
  UniProt ID P30411
• Background: This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation; edema; smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
• Synonyms: B2R; BK-2; BK2; BKR2; BRB2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton