MAT1A Rabbit Polyclonal Antibody

CAT#: TA321125

Anti-MAT1A Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Jurkat cells Primary antibody: TA321125 (MAT1A Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Jurkat cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 16-394 amino acids of human methionine adenosyltransferase I, alpha
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44 kDa
• Gene Name: methionine adenosyltransferase 1A
• Database Link:
  NP_000420
  Entrez Gene 11720 MouseEntrez Gene 25331 RatEntrez Gene 4143 Human
  UniProt ID Q00266
• Background: This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate; which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form; MAT II (gamma); is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
• Synonyms: MAT; MATA1; SAMS; SAMS1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism