E2F3 Goat Polyclonal Antibody

SKU TA321026

Goat Polyclonal Anti-E2F3 (mouse) Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1-3µg/ml
• Reactivity: Mouse (Expected from sequence similarity: Human)
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: C Terminus of NP_034223.1 (DLEKLPLVEDFMCS)
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: E2F transcription factor 3
• Database Link:
  NP_001940
  O00716
• Background: This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
• Synonyms: E2F-3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer