FREM2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | ICC: 20 ug/mL, IF: 20 ug/mL |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | FREM2 antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2. |
| Buffer | FREM2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Concentration | 1ug/ul |
| Purification | FREM2 Antibody is affinity chromatography purified via peptide column. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | FRAS1 related extracellular matrix protein 2 |
| Database Link | |
| Background | FREM2 Antibody: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis. |
| Synonyms | DKFZp686J0811; DKFZp781I048; KIAA1074 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
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