CAVIN3 Rabbit Polyclonal Antibody

CAT#: TA320081

Rabbit Polyclonal PRKCDBP Antibody

Product Images

Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 ??g/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 ug/mL.

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  Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP.
• Formulation: PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: PRKCDBP Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: protein kinase C delta binding protein
• Database Link:
  NP_659477
  Entrez Gene 109042 MouseEntrez Gene 112464 Human
  UniProt ID Q969G5
• Background: PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.
• Synonyms: cavin-3; CAVIN3; HSRBC; SRBC

Reference Data

• Protein Families: Druggable Genome