ORMDL1 Rabbit Polyclonal Antibody

CAT#: TA320079

Rabbit Polyclonal ORMDL1 Antibody

Product Images

Western blot analysis of ORMDL1 in SK-N-SH Cell lysate with ORMDL1 antibody at (A) 1 ug/mL and (B) 2 ug/mL.

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  Immunohistochemistry of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 5 ug/mL.

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  Immunofluorescence of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ORMDL1 antibody was raised against a 16 amino acid synthetic peptide of human ORMDL1.
• Formulation: ORMDL1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ORMDL1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ORMDL sphingolipid biosynthesis regulator 1
• Database Link:
  NP_057551
  Entrez Gene 94101 Human
  UniProt ID Q9P0S3
• Background: ORMDL1 Antibody: The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
• Synonyms: DKFZp686G141; FLJ44364