LEMD1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1 ug/mL |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | LEMD1 antibody was raised against a 19 amino acid synthetic peptide near the center of human LEMD1. |
| Buffer | LEMD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Concentration | 1ug/ul |
| Purification | LEMD1 Antibody is affinity chromatography purified via peptide column. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | LEM domain containing 1 |
| Database Link | |
| Background | LEMD1 Antibody: LEMD1 (LEM domain-containing1) is a member of cancer-testis gene family. LEMD1 is normally expressed only in testis. Six alternatively spliced forms of LEMD1 transcripts in normal testis have been identified, but only one of the six was expressed in colorectal cancers. LEMD1 may represent a promising target antigen for immunotherapy of colorectal cancers. In addition, LEMD1 and SPATA19 are putative cancer biomarkers and promising targets for active immunotherapy. |
| Synonyms | CT50; LEMP-1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease
Sigafoos, Paradise, Fernandez-Zapico
Cancers (Basel) (2021) 13 (14) DOI: 10.3390/cancers13143410
Sigafoos, Paradise, Fernandez-Zapico
Cancers (Basel) (2021) 13 (14) DOI: 10.3390/cancers13143410
Cited by 245
AI Summary: OriGene’s LEMD1 antibody (TA320077) was utilized in this study to investigate the role of LEMD1 in the Hedgehog/GLI signaling pathway, contributing to the analysis of pathway components by enabling specific protein detection.
Snippet: human-specific) CRM1 Santa Cruz (sc-74454) WB, IF, PLA Pan-LAP2 Abcam (ab185718) WB, IF LAP2α Abcam (ab5162) WB, PLA LAP2β BD Biosciences (611000) WB, IF, PLA Emerin Abcam (ab156871) WB, IF Man1 Abcam (ab124148) WB LEMD1 Origene (TA320077
LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription
Mirza, McKellar, Urman et al
Cell (2019) 176 (1-2), 198-212.e15 DOI: 10.1016/j.cell.2018.10.054
Mirza, McKellar, Urman et al
Cell (2019) 176 (1-2), 198-212.e15 DOI: 10.1016/j.cell.2018.10.054
AI Summary: OriGene’s LEMD1 antibody (Cat # TA320077) was used in this study to investigate the role of nuclear envelope proteins in regulating GLI1 transcription factor movement and function.
Snippet: LAP2β BD Biosciences Cat # 611000 Emerin Abcam Cat # ab156871 Man1 Abcam Cat # ab124148 LEMD1 Origene Cat # TA320077 Sun1 Abcam Cat # ab103021 Sun2 Abcam Cat # ab124916 Lamin B1 Abcam Cat # ab90169 Lamin A+C Abcam Cat # ab8984 BANF1 Abcam Cat # ab88464 Acetyl-lysine Cell Signaling Cat # 9441S SuFu Abcam Cat # ab28083 Tubulin DSHB Cat # E7-c
Showing 1-2 of 2 papers.
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