SCUBE1 Rabbit Polyclonal Antibody

SKU TA320028

Rabbit Polyclonal SCUBE1 Antibody

Product Data

• Application: IF, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SCUBE1 antibody was raised against a 14 amino acid synthetic peptide near the center of human SCUBE1.
• Buffer: SCUBE1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SCUBE1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: signal peptide, CUB domain and EGF like domain containing 1
• Database Link:
  NP_766638
  Q8IWY4
• Background: SCUBE1 Antibody: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
• Synonyms: SCUBE1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein