SCUBE2 Rabbit Polyclonal Antibody

SKU TA319990

Rabbit Polyclonal SCUBE2 Antibody

Product Data

• Application: IF, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SCUBE2 antibody was raised against a 17 amino acid synthetic peptide near the center of human SCUBE2.
• Buffer: SCUBE2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SCUBE2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: signal peptide, CUB domain and EGF like domain containing 2
• Database Link:
  NP_066025
  Q9NQ36
• Background: SCUBE2 Antibody: SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
• Synonyms: CEGB1; CEGF1; CEGP1

Reference Data

• Protein Families: Transmembrane