PPHLN1 Rabbit Polyclonal Antibody

CAT#: TA319929

Rabbit Polyclonal Periphilin Antibody

Product Images

Western blot analysis of Periphilin in mouse colon tissue lysate with Periphilin antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of Periphilin in human colon tissue with Periphilin antibody at 2.5 ug/mL.

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  Immunofluorescence of Periphilin in human colon tissue with Periphilin antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 5 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Periphilin antibody was raised against a 16 amino acid synthetic peptide near the center of human Periphilin.
• Formulation: Periphilin Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Periphilin Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: periphilin 1
• Database Link:
  NP_958848
  Entrez Gene 51535 Human
  UniProt ID Q8NEY8
• Background: Periphilin Antibody: Periphilin, known as PPHLN1 or gastric cancer antigen Ga50, plays a role in epithelial differentiation and contributes to epidermal integrity and barrier formation. It interacts with periplakin, a known precursor of the cornified cell envelope. Periphilin 1 is ubiquitously expressed and localizes to nucleus and cytoplasm. Existing as eight alternatively spliced isoforms, Periphilin is highly insoluble and contains a putative nuclear localization signal (NLS) within its N-terminal half, a prerequisite for the formation of insoluble complexes and a possible caspase recognition sequence and a potential nuclear export signal. Periphilin may play an important role in the nervous system.
• Synonyms: CR; HSPC206; HSPC232