CCDC106 Rabbit Polyclonal Antibody

CAT#: TA319903

Rabbit Polyclonal CCDC106 Antibody

Product Images

Western blot analysis of CCDC106 in human brain tissue lysate with CCDC106 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunohistochemistry of CCDC106 in rat brain tissue with CCDC106 antibody at 5 ug/mL.

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  Immunofluorescence of CCDC106 in rat brain tissue with CCDC106 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106.
• Formulation: CCDC106 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: CCDC106 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: coiled-coil domain containing 106
• Database Link:
  NP_037433
  Entrez Gene 232821 MouseEntrez Gene 499071 RatEntrez Gene 29903 Human
  UniProt ID Q9BWC9
• Background: CCDC106 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
• Synonyms: HSU79303; ZNF581