CITED2 Rabbit Polyclonal Antibody

CAT#: TA319813

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Rabbit Polyclonal CITED2 Antibody


Product Datasheet for 'TA319813'


USD 430.00


Availability*
5 Days

Size
    • 100 ug


Product images

Specifications

Product Data
Applications IF, WB
Recommended Dilution WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2.
Formulation CITED2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification CITED2 Antibody is affinity chromatography purified via peptide column.
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 30 kDa
Gene Name Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
Background CITED2 Antibody: CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Synonyms ASD8; MRG-1; MRG1; P35SRJ; VSD2
Reference Data
Protein Families Druggable Genome, Transcription Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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