LCMT2 Rabbit Polyclonal Antibody

CAT#: TA319792

Rabbit Polyclonal TYW4 Antibody

Product Images

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/mL.

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  Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TYW4 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human TYW4.
• Formulation: TYW4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TYW4 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: leucine carboxyl methyltransferase 2
• Database Link:
  NP_055608
  Entrez Gene 296098 RatEntrez Gene 329504 MouseEntrez Gene 9836 Human
  UniProt ID O60294
• Background: TYW4 Antibody: TYW4 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW4 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
• Synonyms: PPM2; TYW4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Androgen and estrogen metabolism, Cardiac muscle contraction, Histidine metabolism, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease, Selenoamino acid metabolism, Tyrosine metabolism