TFEB Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | TFEB antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TFEB. |
Buffer | TFEB Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | TFEB Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | transcription factor EB |
Database Link | |
Background | TFEB Antibody: The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes. |
Synonyms | ALPHATFEB; BHLHE35; TCFEB |
Reference Data |
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