DAP1 (DAP) Rabbit Polyclonal Antibody

SKU
TA319633
Rabbit Polyclonal DAP Antibody
  $640.00
In Stock*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP.
Buffer DAP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification DAP Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 11 kDa; Observed: 11 kDa
Gene Name death-associated protein
Database Link
Background DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
Synonyms MGC99796
Reference Data
Protein Categories Intracellular Proteins
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