AP3S1 Rabbit Polyclonal Antibody

CAT#: TA319631

Rabbit Polyclonal AP3S1 Antibody

Product Images

Western blot analysis of AP3S1 in mouse kidney tissue lysate with AP3S1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of AP3S1 in human kidney tissue with AP3S1 antibody at 2.5 ug/mL.

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  Immunofluorescence of AP3S1 in human kidney tissue with AP3S1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: AP3S1 antibody was raised against a 19 amino acid synthetic peptide near the center of human AP3S1.
• Formulation: AP3S1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: AP3S1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adaptor related protein complex 3 sigma 1 subunit
• Database Link:
  NP_001275
  Entrez Gene 11777 MouseEntrez Gene 302290 RatEntrez Gene 1176 Human
  UniProt ID Q92572
• Background: AP3S1 Antibody: AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.
• Synonyms: CLAPS3; Sigma3A

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome