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GRPR Rabbit Polyclonal Antibody

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SKU
TA316872
GRPR Rabbit Polyclonal (Extracellular Domain) Antibody
Size:
50 ug
Conjugation:
Unconjugated
  $550.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

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LY401638 Transient overexpression lysate of gastrin-releasing peptide receptor (GRPR) (as WB positive control) 100 ug
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View other "GRPR or NM_005314" antibodies

Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC-P (4 µg/ml), WB
Reactivity Bat, Dog, Gibbon, Gorilla, Horse (Predicted: Bovine), Human, Monkey, Pig, Rabbit
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen GRPR antibody was raised against synthetic 18 amino acid peptide from 2nd extracellular domain of human GRPR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Dog, Bat, Horse, Rabbit, Pig (100%); Bovine (94%); Mouse, Rat, Hamster (83%).
Buffer PBS, 0.1% sodium azide.
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name gastrin releasing peptide receptor
Database Link
Synonyms BB2; BB2R
Note Specific for Human GRPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reference Data
Protein Categories GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
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Documents
Resources

file-alt Citations

64Cu-SAR-Bombesin PET-CT Imaging in the Staging of Estrogen/Progesterone Receptor Positive, HER2 Negative Metastatic Breast Cancer Patients: Safety, Dosimetry and Feasibility in a Phase I Trial
Wong, Sheehan-Dare, Nguyen et al
Pharmaceuticals (Basel) (2022) 15 (7) DOI: 10.3390/ph15070772
Cited by 40
AI Summary: In this study, OriGene’s anti-GRPR antibody (Cat# TA336423) was used to assess GRPR expression in metastatic breast cancer biopsy samples, aiding in the evaluation of [64Cu]Cu-SAR-Bombesin PET/CT imaging for staging ER+/PR+/HER2- metastatic breast cancer.
FigureFigureFigure
64Cu-SAR-Bombesin PET-CT Imaging in the Staging of Estrogen/Progesterone Receptor Positive, HER2 Negative Metastatic Breast Cancer Patients: Safety, Dosimetry and Feasibility in a Phase I Trial
Wong, Sheehan-Dare, Nguyen et al
Pharmaceuticals (2022) 15 (7), 772 DOI: 10.3390/ph15070772
Cited by 40
AI Summary: OriGene’s polyclonal antibody TA316872 was used to assess GRPR receptor status in metastatic breast cancer tissue samples, enabling evaluation of target expression relevant to the imaging study.
Snippet: erwent GRPR receptor status staining. Tissue was formalin fixed and paraffin embedded. Mild antigen retrieval was performed using Cell Conditioning for 36 min at 95 °C. Polyclonal antibody TA316872 (OriGene) to GRPR was used at a dilution of 1/200 and incubated at 36 °C for 32 min. Ultraview was used for detection. Slides were scored by a consultant pathologist with cytoplasmic staining as posit
IHC
Showing 1-2 of 2 papers.
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