CD51 (ITGAV) Rabbit Polyclonal Antibody

CAT#: TA314095

Rabbit polyclonal ITGAV (heavy chain, Cleaved-Lys889) antibody

Product Images

Western blot analysis of extracts from A549 cells, treated with etoposide (25uM, 1hour), using ITGAV (heavy chain, Cleaved-Lys889) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:10000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human ITGAV.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit alpha V
• Database Link:
  NP_001138471
  Entrez Gene 3685 Human
  UniProt ID P06756
• Synonyms: CD51; MSK8; VNRA; VTNR
• Note: ITGAV (heavy chain, Cleaved-Lys889) antibody detects endogenous levels of fragment of activated ITGAV resulting from cleavage adjacent to Lys889.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer