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BRCA2 Rabbit Polyclonal Antibody

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SKU
TA313520
Rabbit polyclonal anti-BRCA2 antibody
Size:
100 ul
Conjugation:
Unconjugated
  $380.00
2 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC:1/50-100
Reactivity Human, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from N-terminal of human BRCA2.
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration lot specific
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name BRCA2, DNA repair associated
Database Link
Synonyms BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11
Note BRCA2 antibody detects endogenous levels of total BRCA2 protein.
Reference Data
Protein Categories Cancer: Bladder, Cancer: Brain and CNS, Cancer: Gastrointestinal, Cancer: Gynecologic, Cardiovascular diseases, Cytokines, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Homologous recombination, Pancreatic cancer, Pathways in cancer
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Documents
Resources

file-alt Citations

LINC00261 is an epigenetically-regulated tumor suppressor that is essential for activation of the DNA damage response
Shahabi, Kumaran, Castillo et al
Cancer Res. (2019)
AI Summary: OriGene products contributed to this study by providing the pCMV6-vector backbone (PS100001) for cloning LINC00261 and the LINC00261 shRNA construct (HC137604) for generating stable cell lines to investigate the tumor suppressor role of LINC00261 in lung adenocarcinoma.
Snippet: cloned along with the major exon into the pCMV6-vector backbone (PS100001, Origene). Generation of stable cell lines expressing LINC00261 and were then transfected with either the linearized LINC00261 shRNA construct or scrambled control shRNA (HC137604
Functional Variant Analyses (FVAs) Predict Pathogenicity in the BRCA1 DNA Double-Strand Break Repair Pathway
Loke, Pearlman, Upadhyay et al
Hum. Mol. Genet. (2015)
Cited by 9
AI Summary: OriGene products, specifically the antibodies BRCA1 (TA310042), BRCA2 (TA313520), PALB2 (TA306814), BARD1 (TA313499), and FANCD2 (TA307630), were used for protein co-immunoprecipitation assays to analyze protein interactions in the BRCA1 DNA double-strand break repair pathway in this study.
Snippet: For protein co- immunoprecipitation assays, the following antibodies were used: BRCA1 (Origene TA310042), BRCA2 (Origene TA313520), PALB2 (Origene TA306814), BARD1 (Origene TA313499), FANCD2 (Origene TA307630). ... Cite SaveSaving
IP FC
Showing 1-2 of 2 papers.
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