MEIS2 Goat Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 0.3-1ug/ml |
| Reactivity | Cow), Dog, Mouse, Rat (Expected from sequence similarity: Human |
| Antibody Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence C-QSNRAGFLLDPSVSQ, from the internal region of the protein sequence according to NP_733777.1; NP_733775.1; NP_758526.1. |
| Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20C. Minimize freezing and thawing. |
| Concentration | lot specific |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | Meis homeobox 2 |
| Database Link | |
| Synonyms | HsT18361; MRG1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans
VanOpstall, Perike, Brechka et al
Elife (2020) 9 DOI: 10.7554/eLife.53600
VanOpstall, Perike, Brechka et al
Elife (2020) 9 DOI: 10.7554/eLife.53600
Cited by 1
AI Summary: In this study, OriGene products including the MEIS1 cDNA clone (RC210307), HOXB13 cDNA clone (RC216050), and MEIS1 shRNA lentiviral particles (TL314307V) were used to manipulate gene expression in prostate cancer cells, enabling the authors to demonstrate the tumor-suppressive role of MEIS1 and its dependence on HOXB13.
Snippet: r-posterior axis determination in combination with Homeobox (HOX) genes (Choe et al., 2014;Shanmugam et al., 1999;Williams et al., 2005). Increased expression of MEIS proteins is associated with tumorigenesis in certain cancers, including leukemia (Kumar et al., 2009), ovarian carcinoma (Crijns et al., 2007), and neuroblastoma (Geerts et al., 2005). However, in colorectal carcinoma (Crist et al
Showing 1-1 of 1 papers.
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