beta Actin (ACTB) Mouse Monoclonal Antibody [Clone ID: 8H10]
$375.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 8H10 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:1000 - 1:10000 |
| Reactivity | Dog, Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Beta-actin N-terminal peptide-KLH conjugates |
| Buffer | PBS, pH 7.4 with 0.05% sodium azide. |
| Concentration | lot specific |
| Purification | Affinity purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | actin, beta |
| Database Link | |
| Background | Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. beta actin is one of six different actin isoforms which have been identified. Like GAPDH, ?-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots. |
| Synonyms | BRWS1; PS1TP5BP1 |
| Reference Data | |
| Protein Categories | ADC Targets, Intracellular Proteins |
| Protein Families | ES Cell Differentiation/IPS |
| Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Serine starvation induced APOE expression through promoting RXRB lactylation in tumor-associated macrophages
Ye, Xiong, Luo et al
Communications Biology (2026)
Ye, Xiong, Luo et al
Communications Biology (2026)
Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma
Li, Chen, Gregorova et al
Neoplasia (2025) 70, 101242 DOI: 10.1016/j.neo.2025.101242
Li, Chen, Gregorova et al
Neoplasia (2025) 70, 101242 DOI: 10.1016/j.neo.2025.101242
AI Summary: OriGene contributed to this study by providing the β-actin antibody (TA310155), which was used as a loading control in Western blot experiments to assess protein expression levels.
Snippet: Protein samples were separated by 10% SDS-polyacrylamide gel electrophoresis and subsequently blotted. The antibodies used were the following: β-actin antibody (Origene, Shanghai, China, TA310155), phospho-STAT3 (Ser727) antibody (Cell Signaling Technology, Massachusetts, USA, #9134), STAT3 (124H6)
Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
Liu, Wu, Wu et al
Immunity (2025) 58 (6), 1572-1585.e10 DOI: 10.1016/j.immuni.2025.05.006
Liu, Wu, Wu et al
Immunity (2025) 58 (6), 1572-1585.e10 DOI: 10.1016/j.immuni.2025.05.006
Cited by 34
AI Summary: OriGene’s Anti-human β-Actin antibody (Cat#TA310155) was used in this study as a loading control to ensure accurate protein quantification in experiments analyzing the mechanisms of immune suppression in hepatocellular carcinoma.
Snippet: Anti-human BTK Cell Signaling Technology Cat#3533;RRID: AB_2067811 Anti-human phospho-BTK (Tyr233) Cell Signaling Technology Cat#5082;RRID: AB_10561017 Anti-human β-Actin Origene Cat#TA310155;RRID: AB_10691552 Anti-mouse β-Actin Cell Signaling Technology Cat#8457;RRID: AB_10950489
In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma
Chen, Chen, Xia et al
NPJ Precis Oncol (2025) 9 (1), 10 DOI: 10.1038/s41698-024-00792-7
Chen, Chen, Xia et al
NPJ Precis Oncol (2025) 9 (1), 10 DOI: 10.1038/s41698-024-00792-7
Cited by 2
AI Summary: OriGene’s β-actin antibody (cat #TA310155) was used as a loading control in western blot experiments to assess protein expression in this study.
Snippet: ignaling Technology, cat #9661), c-Myc (Cell Signaling Technology, cat #18583), phospho-c-Myc (Ser62) (Cell Signaling Technology, cat #13748), α-tubulin (Abcam, cat #ab4074), β-actin (OriGene, cat #TA310155), and GAPDH (Millipore, cat #CB1001) overnight at 4 °C. …
TH301 Emerges as a Novel Anti-Oncogenic Agent for Human Pancreatic Cancer Cells: The Dispensable Roles of p53, CRY2 and BMAL1 in TH301-Induced CDKN1A/p21CIP1/WAF1 Upregulation
Farmakis, Stravopodis, Prombona
IJMS (2024) 26 (1), 178 DOI: 10.3390/ijms26010178
Farmakis, Stravopodis, Prombona
IJMS (2024) 26 (1), 178 DOI: 10.3390/ijms26010178
Cited by 4
AI Summary: OriGene products, specifically the β-Actin antibody (#TA310155) and CRY2 antibody (#TA502905S), were used as key reagents for Western blot analysis to assess protein expression changes in pancreatic cancer cells treated with TH301 in this study.
Snippet: (β-Actin) (Origene Technologies, Rockville, MD, USA;#TA310155), and CRY2 (Origene Technologies, #TA502905S). After incubation with the respective HRP-conjugated Secondary Antibody (Anti-rabbit IgG, #7074;Anti-mouse IgG, #7076;Cell Signaling Technology), signals were detected using the Immobilon Classico Western HRP Substrate (Merck-Millipore, Burlington, MA, USA) and obtained images were acquired by the Fujifilm LAS-4000 Imaging System (Fujifilm Corporation, Tokyo, Japan). …
TH301, a Circadian Clock Modulator, Emerges as a Novel Anti-oncogenic Agent for Human Pancreatic Cancer Cells: the Dispensable Roles of p53, CRY2 and BMAL1 in TH301-induced CDKN1A/p21CIP1/WAF1 Upregulation
Farmakis, Stravopodis, Prombona
preprint (2024)
Farmakis, Stravopodis, Prombona
preprint (2024)
Snippet: Cell Signaling Technology, Danvers, Massachusetts, USA;#13418), CRY2 (1:200;Origene Technologies, Rockville, Maryland, USA;#TA502905S), Phospho-Histone H2A.X (γH2AX) (1:500;#9718) and beta-Αctin (β-Actin) (1:2,000/1:500;#14020;#TA310155). After incubation with the respective HRPconjugated Secondary Antibody (1:2,000;Anti-rabbit IgG, #7074;1:2,000, Anti-mouse IgG, #7076;Cell
Showing 1-6 of 18 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
