GAPDH Mouse Monoclonal Antibody [Clone ID: 1D4]
Specifications
| Product Data | |
| Clone Name | 1D4 |
|---|---|
| Application | WB |
| Recommended Dilution | WB |
| Reactivity | Dog, Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Purified pig GAPDH |
| Buffer | PBS, pH 7.4 with 0.05% sodium azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | glyceraldehyde-3-phosphate dehydrogenase |
| Database Link | |
| Background | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots. |
| Synonyms | G3PD; GAPD; HEL-S-162eP |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins |
| Protein Families | ES Cell Differentiation/IPS |
| Protein Pathways | Alzheimer's disease, Glycolysis / Gluconeogenesis, Metabolic pathways |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease
Pan, Yang, Wang et al
Int J Mol Med (2026) 57 (2) DOI: 10.3892/ijmm.2025.5714
Pan, Yang, Wang et al
Int J Mol Med (2026) 57 (2) DOI: 10.3892/ijmm.2025.5714
Cited by 2
AI Summary: OriGene’s anti-GAPDH antibody (cat. no. TA310153) was used in this study as a loading control for immunoblotting, contributing to the validation of protein expression changes during investigation of autophagy-mediated degradation of PFKFB3 in intestinal epithelial cells.
Snippet: anti-lactate dehydrogenase (LDHA;cat. no. ab52488) and anti-PFKFB3 (cat. no. ab181861) from Abcam;anti-GAPDH (cat. no. TA310153) from OriGene Technologies, Inc.;anti-Claudin-5 (cat. no. AF5216) from Affinity Biosciences;anti-Claudin-8 (cat. no. GTX77832) from GeneTex, Inc.;anti-K48-linkage specific ubiquitin (cat. no. bsm-63005R)
IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis
Travers, Rochman, Caldwell et al
Sci Rep (2017) 7 (1), 17563 DOI: 10.1038/s41598-017-17541-5
Travers, Rochman, Caldwell et al
Sci Rep (2017) 7 (1), 17563 DOI: 10.1038/s41598-017-17541-5
AI Summary: OriGene products contributed to this study by providing mouse anti-HSP90 (TA500494) and mouse anti-GAPDH (TA310153) primary antibodies, which were used as controls in the protein expression analyses.
Snippet: Mouse anti-HSP90 (TA500494) and mouse anti-GAPDH (TA310153) primary antibodies were purchased from Origene (Rockville, MD)
Showing 1-2 of 2 papers.
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