RUNX2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | FC, ICC/IF, IHC |
|---|---|
| Recommended Dilution | Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:50-1:100, Flow Cytometry: 2-5 ug/ml |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide made to an internal region of the human RUNX2 protein (within residues 225-300). Swiss-Prot Q13950 |
| Buffer | PBS, 30% glycerol and 0.05% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | runt related transcription factor 2 |
| Database Link | |
| Synonyms | AML3; CBFA1; CCD; CCD1; OSF-2; OSF2; PEA2aA; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
TLR2 Promotes Vascular Smooth Muscle Cell Chondrogenic Differentiation and Consequent Calcification via the Concerted Actions of Osteoprotegerin Suppression and IL-6-Mediated RANKL Induction
Lee, Yeh, Wu et al
Arterioscler Thromb Vasc Biol (2019) 39 (3), 432-445 DOI: 10.1161/ATVBAHA.118.311874
Lee, Yeh, Wu et al
Arterioscler Thromb Vasc Biol (2019) 39 (3), 432-445 DOI: 10.1161/ATVBAHA.118.311874
AI Summary: In this study, OriGene's TLR2 shRNA lentiviral particles and mouse TLR2 overexpression plasmid were used to manipulate TLR2 expression in vascular smooth muscle cells, enabling the authors to investigate TLR2's role in promoting chondrogenic differentiation and vascular calcification.
Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing
Liu, Carrera, Flamini et al
Bone (2018) 108, 145-155 DOI: 10.1016/j.bone.2017.12.027
Liu, Carrera, Flamini et al
Bone (2018) 108, 145-155 DOI: 10.1016/j.bone.2017.12.027
Cited by 74
AI Summary: In this study, OriGene’s Mouse Ki67 (MKI67) monoclonal antibody (TA500711) was used to assess cellular proliferation during cortical defect repair, contributing to the evaluation of how mechanical loading affects bone healing processes.
Wnt signaling regulates homeostasis of the periodontal ligament
Lim, Liu, Cheng et al
J. Periodont. Res. (2014)
Lim, Liu, Cheng et al
J. Periodont. Res. (2014)
Cited by 89
AI Summary: OriGene’s Runx2 antibody was used in this study to assess osteogenic protein expression, helping to reveal that Wnt signaling is essential for maintaining periodontal ligament homeostasis.
Snippet: The antibodies used include Runx2 (OriGene, Rockville, MD, USA;1 : 2000 dilution), osteopontin (NIH LF 175, Bethesda, MD, USA;1 : 4000 dilution), fibromodulin (Santa Cruz Biotech, Santa Cruz, CA, USA;1 : 1000 dilution) and β-catenin (Lab Vision, Värmdö, Sweden ... Cite SaveSaving
Showing 1-3 of 3 papers.
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