OGG1 Rabbit Polyclonal Antibody

SKU
TA309779
Rabbit Polyclonal Ogg1 Antibody
  $680.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, FC, ICC/IF, IHC, Immunoblotting, IP, WB
Recommended Dilution ELISA, Immunohistochemistry-Frozen: 1:25-1:100, Immunohistochemistry, Flow (Intracellular), Immunohistochemistry-Paraffin, Immunoprecipitation: 1:10-1:500, Immunoblotting, Flow Cytometry, Western Blot: 1:500-1:1000, Immunocytochemistry/ Immunofluorescence: 1:100 - 1:200
Reactivity Human, Primate, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen A peptide derived from the human Ogg1 (within amino acids 1-100).
Buffer Tris-citrate/phosphate buffer, pH 7 to 8 and 0.09% Sodium Azide
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name 8-oxoguanine DNA glycosylase
Database Link
Synonyms HMMH; HOGG1; MUTM; OGH1
Reference Data
Protein Categories Cancer: Bladder, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Base excision repair
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Documents
Resources

file-alt Citations

Mechanism underlying the effect of long-term exposure to low dose of pesticides on DNA integrity
Alleva, Manzella, Gaetani et al
Environ. Toxicol. (2018)
AI Summary: OriGene’s anti-OGG1 antibody was used in this study to detect and analyze OGG1 protein expression, enabling the investigation of DNA repair mechanisms affected by long-term low-dose pesticide exposure.
Snippet: The cell lysate protein (50 µg per lane) was resolved using 4%-12% SDS-PAGE (Life Technologies), and transferred to nitrocellulose membranes, and incubated overnight with anti-OGG1 (Origene, Rockville, MD). Actin (Bethyl, Montgomery, TX) was used as loading
Organic honey supplementation reverses pesticide-induced genotoxicity by modulating dna damage response
Alleva, Manzella, Gaetani et al
Mol Nutr Food Res (2016)
Cited by 28
AI Summary: In this study, the anti-OGG1 antibody from OriGene was used to detect DNA repair protein levels, helping to assess how organic honey supplementation modulates DNA damage response following pesticide exposure.
Snippet: (50 µg per lane) were resolved using 4-12% SDS-PAGE (Life Technologies), and transferred to nitrocellulose membranes, and incubated overnight with anti-NRF2 (Cell Signaling Technology, Danvers, MA) and anti-OGG1 (Origene, Rockville, MD). Lamin (Bethyl, ... Cite SaveSaving
WB
Circadian Modulation of 8-Oxoguanine DNA Damage Repair
Manzella, Bracci, Strafella et al
Sci Rep (2015) 5, 13752 DOI: 10.1038/srep13752
Cited by 74
AI Summary: OriGene’s total RNA isolation kit was used to extract RNA for gene expression analysis, enabling the researchers to assess circadian variations in Ogg1 expression in the study.
Snippet: Gene expression analysis. The isolation of total RNA was performed (OriGene, Rockville, MD, USA) according to the manufacturer's instructions. RNA quality and quantification were evaluated with a Nanodrop 1000 spectrophotometer (Thermo Scientific, Wilmington ... Cite SaveSaving
FigureFigureFigure
Wood dust exposure induces cell transformation through EGFR-mediated OGG1 inhibition
Staffolani, Manzella, Strafella et al
Mutagenesis (2015)
Cited by 18
AI Summary: In this study, OriGene's LC3B and OGG1 antibodies were used to assess autophagy and DNA repair protein expression, helping demonstrate that wood dust exposure impairs DNA repair and promotes cell transformation.
Snippet: samples (50 µg per lane) were resolved using 12.5% SDS–PAGE, and transferred to nitrocellulose membranes, and incubated overnight with anti-EGFR, pAKT, AKT (Cell Signaling Technology, Danvers, MA, USA), pmTOR, mTOR, LC3B and OGG1 (Origene, Rockville ... Cite SaveSaving
WB
Showing 1-4 of 4 papers.
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