GALNT7 Rabbit Polyclonal Antibody
SKU
TA309013
Rabbit Polyclonal antibody to GALNT7 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7))
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000 |
Reactivity | Human, Mouse (Predicted: Rat, X. tropicalis), Zebrafish |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 24 and 515 of GALNT7 (Uniprot ID#Q86SF2) |
Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 75 kDa |
Gene Name | polypeptide N-acetylgalactosaminyltransferase 7 |
Database Link | |
Background | This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq] |
Synonyms | GALNAC-T7; GalNAcT7 |
Note | Seq homology of immunogen across species: Rat (96%), Zebrafish (82%), Xenopus tropicalis (82%) |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, O-Glycan biosynthesis |
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