ADAMTSL2 Rabbit Polyclonal Antibody

CAT#: TA308981

Rabbit polyclonal antibody to ADAMTSL2 (ADAMTS-like 2)

Product Images

Sample (30 ug of whole cell lysate). A:H1299. 7.5% SDS PAGE. TA308981 diluted at 1:500

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  ADAMTSL2 antibody [C3], C-term detects ADAMTSL2 protein at cytosol (secreted) on SkHep1xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep1xenograft. ADAMTSL2 antibody [C3], C-term (TA308981) dilution: 1:500.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 796 and 951 of ADAMTSL-2 (Uniprot ID#Q86TH1)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 105 kDa
• Gene Name: ADAMTS like 2
• Database Link:
  NP_001138792
  Entrez Gene 77794 MouseEntrez Gene 9719 Human
  UniProt ID Q86TH1
• Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq]
• Synonyms: GPHYSD1
• Note: Seq homology of immunogen across species: Mouse (100%), Bovine (100%)

Reference Data

• Protein Families: Secreted Protein