SUCLA2 Rabbit Polyclonal Antibody

SKU
TA308975
Rabbit Polyclonal antibody to SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit)
  $665.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:20000
Reactivity Bovine, Human, Mouse (Predicted: Rat, X. tropicalis), Xenopus, Zebrafish
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 138 and 416 of SUCLA2 (Uniprot ID#Q9P2R7)
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 50 kDa
Gene Name succinate-CoA ligase ADP-forming beta subunit
Database Link
Background Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. provided by RefSeq
Synonyms A-BETA; MTDPS5; SCS-betaA
Note Seq homology of immunogen across species: Rat (88%), Xenopus laevis (85%), Zebrafish (81%), Bovine (92%), Xenopus tropicalis (83%)
Reference Data
Protein Categories Enzyme: Ligase, Intracellular Proteins
Protein Pathways Citrate cycle (TCA cycle), Metabolic pathways, Propanoate metabolism
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