GLDC Rabbit Polyclonal Antibody
CAT#: TA308885
Rabbit Polyclonal antibody to Glycine dehydrogenase (glycine dehydrogenase (decarboxylating))
USD 436.00
USD 200.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000 |
Reactivities | Human (Predicted: Mouse, Chicken, Rat, Xenopus, Bovine) |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 442 and 723 of Glycine dehydrogenase (Uniprot ID#P23378) |
Formulation | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 113 kDa |
Gene Name | glycine decarboxylase |
Database Link | |
Background | The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331. [supplied by OMIM] |
Synonyms | GCE; GCSP; HYGN1 |
Note | Seq homology of immunogen across species: Mouse (91%), Chicken (85%), Rat (84%), Xenopus laevis (86%), Bovine (92%) |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Glycine, serine and threonine metabolism, Metabolic pathways |
Documents
Product Manuals |
FAQs |
SDS |
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