FMO1 Rabbit Polyclonal Antibody

SKU
TA308880
Rabbit polyclonal antibody to FMO1 (flavin containing monooxygenase 1)
  $665.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB:1:500-1:3000
Reactivity Bovine), Dog, Human (Predicted: Mouse, Pig, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 437 of FMO1 (Uniprot ID#Q01740)
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 60 kDa
Gene Name flavin containing monooxygenase 1
Database Link
Background Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. provided by RefSeq
Synonyms Flavin-containing monooxygenase 1 (fetal liver); flavin containing monooxygenase 1; OTTHUMP00000033536; OTTHUMP00000033537
Note Seq homology of immunogen across species: Mouse (83%), Dog (88%), Pig (86%), Rat (82%), Bovine (85%)
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome
Protein Pathways Drug metabolism - cytochrome P450
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