ACTC1 Rabbit Polyclonal Antibody
SKU
TA308841
Rabbit Polyclonal antibody to alpha Actin (cardiac muscle) (actin, alpha, cardiac muscle 1)
$665.00
5 Days*
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:10000 |
| Reactivity | Bovine, Human, Mouse (Predicted: Chicken, Pig, X. tropicalis), Xenopus |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment contain a sequence corresponding to a region within amino acids 99 and 354 of alpha Actin (cardiac muscle) (Uniprot ID#P68032) |
| Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
| Concentration | lot specific |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 42 kDa |
| Gene Name | actin, alpha, cardiac muscle 1 |
| Database Link | |
| Background | Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). provided by RefSeq |
| Synonyms | ACTC; ASD5; CMD1R; CMH11; LVNC4 |
| Note | Seq homology of immunogen across species: Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Chicken (100%), Bovine (100%) |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
| Protein Pathways | Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Extracellular vesicles (EVs): A promising therapeutic tool in the heart tissue regeneration
Diomede, Guarnieri, Lanuti et al
Biofactors (2023)
Diomede, Guarnieri, Lanuti et al
Biofactors (2023)
Cited by 6
AI Summary: OriGene contributed to this study by providing the anti-ACTC1 antibody (TA308841), which was used to assess cardiomyogenic differentiation in human dental pulp stem cells through immunofluorescence analysis.
Snippet: Mesenchymal stem cells (MSCs) treatment has been widely explored as a therapy for myocardial infarction, peripheral ischemic vascular diseases, dilated cardiomyopathy Save;The primary antibodies used in the study were as follows: anti-GATA4 (1:200) (sc-25310, Santa Cruz Biotechnology, Dallas, TX, USA), anti-ACTC1 (1:200) (TA308841, Origene, Rockville, MD, USA), anti-CX43 (1:200) (sc-13558, Santa Cruz Biotechnology), and anti-NKx2.5 (1:200) (sc-376565, Santa Cruz Biotechnology)
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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