DOCK1 Rabbit Polyclonal Antibody

SKU TA308798

Rabbit Polyclonal antibody to DOCK1 (dedicator of cytokinesis 1)

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivity: Human (Predicted: Mouse, Rat, Zebrafish)
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1802 and 1865 of DOCK1
• Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 215 kDa
• Gene Name: dedicator of cytokinesis 1
• Database Link:
  NP_001371
  Q14185
• Background: This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis. [provided by RefSeq]
• Synonyms: ced5; DOCK180
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (92%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Focal adhesion, Regulation of actin cytoskeleton