C5L2 (C5AR2) Rabbit Polyclonal Antibody

SKU
TA308708
Rabbit polyclonal antibody to GPR77 (G protein-coupled receptor 77)
  $665.00
5 Days*
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB:1:500-1:3000
Reactivity Human (Predicted: Bovine)
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region within amino acids 248 and 337 of GPR77 (Uniprot ID#Q9P296)
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 36 kDa
Gene Name complement component 5a receptor 2
Database Link
Background The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 PubMed 16204243). supplied by OMIM
Synonyms C5L2; GPF77; GPR77
Note Seq homology of immunogen across species: Bovine (86%)
Reference Data
Protein Categories GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
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