IDI1 Rabbit Polyclonal Antibody

CAT#: TA308665

Rabbit polyclonal antibody to IDI1 (isopentenyl-diphosphate delta isomerase 1)

Product Images

Sample (30 ug of whole cell lysate). A: Molt-4. 12% SDS PAGE. TA308665 diluted at 1:3000.

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  Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using IDI1 (TA308665) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Rat, Xenopus, Zebrafish, Bovine, X. tropicalis)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 173 of IDI1 (Uniprot ID#Q13907)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: isopentenyl-diphosphate delta isomerase 1
• Database Link:
  NP_004499
  Entrez Gene 89784 RatEntrez Gene 319554 MouseEntrez Gene 3422 Human
  UniProt ID Q13907
• Background: IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq]
• Synonyms: IPP1; IPPI1
• Note: Seq homology of immunogen across species: Mouse (87%), Rat (85%), Xenopus laevis (80%), Zebrafish (81%), Bovine (89%), Xenopus tropicalis (81%)

Reference Data

• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis