ING5 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB:1:500-1:3000 |
Reactivity | Bovine, Chicken, Human (Predicted: Rat, Mouse), Rhesus Monkey, X. tropicalis, Xenopus |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region within amino acids 46 and 142 of ING5 (Uniprot ID#Q8WYH8) |
Buffer | 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 28 kDa |
Gene Name | inhibitor of growth family member 5 |
Database Link | |
Background | The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq] |
Synonyms | p28ING5 |
Note | Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%) |
Reference Data | |
Protein Families | Druggable Genome |
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